Everton made hard work of Rotherham United in the last round, so you can expect Carlo to name a strong a team as possible as the Owls visit Goodison Park for the first time since 2000.
So how will be Blues line-up?
The good news is that Dominic Calvert-Lewin is back available after a hamstring issue ruled him out of the last two matches.
However, the likes of Lucas Digne, Jean-Phillipe Gbamin, Allan, Fabian Delph, Alex Iwobi and Niels Nkounkou will all miss out here.
That leaves Everton a little bit threadbare on the bench, so there could be an opportunity for a new under-23s face to make the matchday squad, with Jarrod Branthwaite and Ellis Simms now out on loan.
Tactics and Formation
4-2-3-1 has been the preferred set-up of late, but with Lucas Digne and Niels Nkounkou ruled out, we’ll probably see Ben Godfrey sitting at left-back.
Elsewhere it’ll be as you would expect, although Carlo Ancelotti has to choose between Jordan Pickford and Robin Olsen, Mason Holgate and Yerry Mina, plus Tom Davies or Andre Gomes.
Starters (likelihood of starting rated out of 10)
Robin Olsen – 6/10
Olsen’s turn if the rotation continues.
Seamus Coleman – 9/10
Ben Godfrey – 9/10
Carlo confirmed both Digne and Nkounkou will miss this one, so it’ll probably be Godfrey back at left-back.
Mason Holgate – 8/10
Michael Keane – 9/10
Abdoulaye Doucoure – 10/10
The midfielder is suspended for Leicester, and also really turned it around when he came on against the Millers in the previous round.
Tom Davies – 7/10
Another toss-up between Davies and Gomes, but would edge for Davies given he provides more defensive cover.
James Rodriguez – 9/10
Gylfi Sigurdsson – 8/10
Richarlison – 9/10
Dominic Calvert-Lewin – 9/10
Tyler Onyango – With several players ruled out and Branthwaite and Simms now out on loan, Tyler Onyango (or possibly Beni Baningime) may make the first team matchday squad for the first time.