Marco Silva’s first competitive home game in charge of Everton sees him take on Mark Hughes’ Southampton.
Both sides have one point on the board after opening weekend draws. The Toffees drew 2-2 at newly-promoted Wolves while Southampton were held to a goalless draw by Burnley.
Everton will be without Phil Jagielka following his red card last weekend but Richarlison, Bernard, Kurt Zouma and Lucas Digne could all make their home debuts.