After the 3-0 romp at Goodison Park, manager Ronald Koeman spoke about the minor hamstring issue that the Republic of Ireland midfielder came up with, expressing his disappointment with the niggling nature of those injuries.
"James, again, he has some problems on his hamstring. It happened at the beginning of last week, that is really painful for himself but also for me because I like him and we like to progress with, continue with James.
"It is not a big hamstring, maybe he will be out for one or two weeks, but I am really disappointed about that. "But we need to deal with his fitness and after 30-35 minutes, like last week, we need to put him in the recovery group after the game.
"That is what we need to learn. I am not a doctor, I am not a medical person but what I like is the best for him.
"This is another step back for the boy, that is really disappointing."
Leighton Baines left the game at the half with an unnamed injury, which Koeman later clarified was related to his back.
"Leighton had a problem with his back, he couldn't move anymore, that was the reason we had to change Leighton."
The next international break starts after next weekend’s game against Hull City, and there was an outside chance that Baines would have made the English squad with Gareth Southgate watching today, but that is unlikely now.